… Abstract: Upon the completion of the Human Genome Project, scientists have been trying to
… lyze all regulatory elements in the human genome. Taking advantage of the development of …

… a few percent of the total human genome, while the rest of the noncoding genome does not
… -increasing amount of publicly available data from human genetic and genomic studies. The …

… 1.1 sci‑ATAC及其衍生技术 2015 年,Cusanovich 等[6]提出了单细胞组合 索引分析染色质可及
性(single cell combinatorial indexing assay for transposase accessible chromatin, sci‑ ATAC‑…

… The chromatin accessibility landscape of primary human cancers. … and genome engineering
to understand the functional relevance of SNPs in non-coding regions of the human genome…

… for study of genome-wide mapping for chromatin accessibility, … of the epigenetic and genetic
regulatory networks using the … The accessible chromatin landscape of the human genome. …

… The genomic era began in 2001 with the decoding of the first human genome. This was the
biggest collaborative biology research initiative in the world. It allowed scientists to see the …

… a chicken chromatin accessibility atlas using 53 Assay of Transposase Accessible Chromatin
… An average of 50 796 open chromatin regions were identified per sample, cumulatively …

… Charting a dynamic DNA methylation landscape of the human genome. Nature, 2013, 500(…
The accessible chromatin landscape of the human genome. Nature, 2012, 489(7414): 75–…

… mechanisms, particularly DNA methylation. This review comprehensively surveys recent
human-centered studies that investigate whole genome DNA methylation in Alzheimer’s …

… A 3D map of the human genome at kilobase resolution reveals principles of chromatin looping.
Cell, 2014, 159(7): 1665–1680. [DOI] [23] Nagano T, Lubling Y, Stevens TJ, Schoenfelder …