… the latency-associated peptide (LAP) of the latent TGF-β complex also interacts with
thrombospondin-1 … formation involves the activation sequence of thrombospondin-1 (KRFK) and a …

… of a 278 amino acid pro-peptide, known as the latency associated peptide (LAP), that is non-…
In order to better characterize TSP-LAP interactions, we sought to identify a site in the LAP …

… that the latency-associated peptide (LAP) of the latent TGF-P complex also interacts with
TSP-… formation involves the acti vation sequence of TSP-1 (KRFK) and a sequence (LSKL) near …

… binds to the TGF-β small latent complex comprised of the N-terminal latency associated peptide
… The C-terminus of the mature TGF-β homodimer binds to TGF-β signaling receptors. The …

… to peptide 246, and addition of the peptide to CD3-activated … These data suggest that, at best,
the 246 peptide interacts … Prior to secretion, the N-terminal latency-associated peptide (LAP…

… TGF-β1 activation is a multistep process. The TGF-β1 precursor interacts with a latency-associated
peptide and forms a complex called small latent complex. The small latent complex …

… by an intermolecular activation way provokes the release of … N-terminal of the latency
associated peptide (LAP) and leads to … -containing peptide and we also evidenced that …

… as a latent complex with latency associated peptide (LAP) non-… We previously showed
that thrombospondin 1 (TSP1) is a … through specific molecular interactions (9, 10). The KRFK …

… association with the latency-associated peptide (LAP) [15]. The activating function of TSP-1 …
They contain amino acid sequences that interact with the neutrophil elastase, and upon this …

… peptides did not reduce LAP-mediated chemotaxis (Table 1). Because thrombospondin-1
interacts … is important for latent TGF-β1 activation and interacts directly with a defined region of …