The biological properties of cetuximab

B Vincenzi, G Schiavon, M Silletta, D Santini… - Critical reviews in …, 2008 - Elsevier
cetuximab is able to inhibit growth of epidermal growth factor receptor (EGFR)-expressing
tumour cells in vitro. Moreover, treatment with cetuximab … linked to cetuximab biological effects …

Vaccination with cetuximab mimotopes and biological properties of induced anti–epidermal growth factor receptor antibodies

AB Riemer, H Kurz, M Klinger… - Journal of the …, 2005 - academic.oup.com
cetuximab-like” antibodies in vivo using the mimotope approach. Methods: We used the phage
display technique to identify four peptides structurally mimicking the cetuximabcetuximab

Evaluation of the physicochemical and biological stability of cetuximab under various stress condition

A Farjami, M Siahi-Shadbad… - … of Pharmacy & …, 2019 - journals.library.ualberta.ca
… To conclude, physicochemical and biological characterization of cetuximab exposed to …
do not influence physicochemical and biological properties of cetuximab. The mild stress …

A critical review of properties and analytical/bioanalytical methods for characterization of Cetuximab

G Hanck-Silva, LN Fatori Trevizan… - Critical reviews in …, 2020 - Taylor & Francis
Cetuximab (CTX) is a chimeric monoclonal antibody (mAb) able to selectively bind to the
epidermal growth factor receptor (EGFR), resulting in inhibition of EGF linkage and …

[PDF][PDF] Cetuximab: from bench to bedside

B Vincenzi, A Zoccoli, F Pantano… - Current cancer drug …, 2010 - researchgate.net
… Moreover, numerous clinical trials demonstrated cetuximab … data on biological properties
of cetuximab focusing on the … clinical data on biological properties of cetuximab focusing on …

Cetuximab: a review of its use in squamous cell carcinoma of the head and neck and metastatic colorectal cancer

SKA Blick, LJ Scott - Drugs, 2007 - Springer
… trials comparing cetuximab with other biological agents will help to establish definitively
the role of cetuximab in the management of SCCHN and mCRC. In the meantime, cetuximab, …

Aerodynamical, immunological and pharmacological properties of the anticancer antibody cetuximab following nebulization

A Maillet, N Congy-Jolivet, S Le Guellec… - Pharmaceutical …, 2008 - Springer
… out a potential loss of activity of the cetuximab contained in the aggregates since the
biological effects observed might only be due to the soluble fraction of cetuximab in the solution. …

Clinical drug development of cetuximab, a monoclonal antibody

A Nolting, FE Fox, A Kovar - … and pharmacodynamics of biotech …, 2006 - Wiley Online Library
… Although anti-cetuximab antibodies were identified in some patients, they were found not to
interfere with the biological properties of cetuximab, such as its ability to bind EGFR (ie, they …

[HTML][HTML] … the stability of cetuximab (Erbitux®) and panitumumab (Vectibix®): An orthogonal assessment of physicochemical, biological and microbiological properties …

D Carpanese, V Rossi, V Di Paolo, L Quintieri… - International Journal of …, 2024 - Elsevier
… According to the SmPCs, cetuximab is stable for 48 h at 25 C after dilution and the opened
… of cetuximab and panitumumab in terms of maintenance of their physiochemical, biological, …

Cetuximab: preclinical evaluation of a monoclonal antibody targeting EGFR for radioimmunodiagnostic and radioimmunotherapeutic applications

DE Milenic, KJ Wong, KE Baidoo, GL Ray… - Cancer biotherapy & …, 2008 - liebertpub.com
… unmodified cetuximab or cetuximab-CHX-A-DTPA conjugate were added to the wells in
triplicate, one set of wells received BSA/PBS without any competitor, along with 125I-cetuximab (…