The clinical and microbiological correlates of premature rupture of membranes

C Karat, P Madhivanan, K Krupp, S Poornima… - Indian journal of medical …, 2006 - Elsevier
Prematurity is the cause of 85% of neonatal morbidity and mortality. Premature rupture of the
membranes (PROM) is associated with 30-40% of preterm deliveries. A case-control study
conducted between July 2002 and 2003 examined the correlates and risk factors for PROM
in Mysore, India. WBCs in vaginal fluid, leucocytes in urine, UTI and infection with E. coli, S.
aureus, C. albicans and BV were significantly associated with PROM. BV, E. coli and WBCs
in vaginal fluid were independent risk factors. Screening and treatment of BV and E. coli …
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