The commensal infant gut meta-mobilome as a potential reservoir for persistent multidrug resistance integrons
Despite the accumulating knowledge on the development and establishment of the gut
microbiota, its role as a reservoir for multidrug resistance is not well understood. This study
investigated the prevalence and persistence patterns of an integrase gene (int1), used as a
proxy for integrons (which often carry multiple antimicrobial resistance genes), in the fecal
microbiota of 147 mothers and their children sampled longitudinally from birth to 2 years.
The study showed the int1 gene was detected in 15% of the study population and apparently …
microbiota, its role as a reservoir for multidrug resistance is not well understood. This study
investigated the prevalence and persistence patterns of an integrase gene (int1), used as a
proxy for integrons (which often carry multiple antimicrobial resistance genes), in the fecal
microbiota of 147 mothers and their children sampled longitudinally from birth to 2 years.
The study showed the int1 gene was detected in 15% of the study population and apparently …
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