Background: Radiation-induced oral mucositis (RIOM) poses a significant challenge in the
management of head and neck cancer patients (HNCs). Patients may require adjustments in
their cancer treatment, such as dose reductions or treatment delays, which can decrease the
effectiveness of the antineoplastic therapy. Numerous clinical investigations have
demonstrated that curcumin, an herbal agent, exhibits a wide range of pharmacologic
actions, including anti-inflammatory, antibacterial, and anticarcinogenic effects and the …