疫苗異源接種對SARS-CoV-2 變異株體液免疫反應之研究

SM Ieong - 國立臺灣大學醫學檢驗暨生物技術學系學位論文, 2022 - airitilibrary.com
… , evolving mutations in the SARS-CoV-2 spike protein have led … neutralizing antibody
responses against SARS-CoV-2 VOCs than the two-dose regimens. Nevertheless, the neutralizing

新型冠状病毒的变异株进展: 起源, 变异动力与防控措施

沈佳莹, 林剑生, 曹广文 - 上海预防医学, 2022 - sjpm.org.cn
… emergence of SARS-CoV-2 variants is generally considered as the outcome of a“mutation-…
transmissibility,decreasing reactivity to the neutralizing antibodies,immune escape,and …

[PDF][PDF] SARS-CoV-2 刺突糖蛋白突变体与血管紧张素转化酶2 结合的热点残基分析

马学婧, 李俊甫, 张兆英, 白静, 李末 - 生命科学研究 - smkx.hunnu.edu.cn
… of SARS-CoV-2 spike variants would be helpful in designing neutralizing antibodies and …
To address this need, we analyzed how amino acid mutations in SARSCoV-2 RBD would affect

刺突蛋白的突变和血管紧张素转化酶2 的等位基因变异对SARS-CoV-2 靶向治疗策略的影响

CJ Shu, X Huang, HH Tang, DD Mo, JW Zhou… - Zoological …, 2021 - zoores.ac.cn
Mutations in spike protein and allele variations in ACE2 impact targeted therapy strategies
against SARS-CoV-2 … 在本研究中,我们探索了ACE2和spike作为靶点开发抗SARS-CoV-2病毒…

[HTML][HTML] SARS-CoV-2 Omicron 变异株的研究进展

王康泓 - Advances in Microbiology, 2022 - hanspub.org
… 2 (SARS-CoV-2) with strong mutation ability has continuously mutated and evolved during
… 早在2020年1月,一种刺突蛋白(spike protein, S)携带D614G突变的SARS-CoV-2毒株因其更强…

[PDF][PDF] SARS-CoV-2 奥密克戎变异株的研究进展

刘宏, 凌子旭, 张净, 李思雨, 白天科… - 中国比较医学 …, 2022 - zgbjyx.cnjournals.com
… of the SARSCoV-2 Delta variant, key spike mutations and immune … High genetic barrier to
SARS-CoV-2 polyclonal neutralizingSARS-CoV-2 neutralizing antibody structures inform …

利用腺相關病毒載體表現對新冠病毒突變株有廣泛保護效果的抗人類ACE2 黏膜抗體

SI Tsung - 國立臺灣大學微生物學研究所學位論文, 2023 - airitilibrary.com
… therapies targeting the viral spike protein, which prevents the … , harboring numerous
mutations in the spike protein have … ch2H2 antibody in preventing SARS-CoV-2 infection in the …

新冠病毒Mu 突变株对灭活疫苗诱导抗体具有显著增强的免疫逃逸

X Xie, JB Han, G Ma, XL Feng, X Li, QC Zou… - Zoological …, 2021 - zoores.ac.cn
… on a global scale, in part due to newly emerging SARS-CoV-2 … variant pseudovirus (containing
D614G spike mutation); B.… -change in neutralization resistance of indicated spike variants …

[PDF][PDF] 新冠病毒刺突糖蛋白结构与功能的生物信息学分析及原核表达

徐本锦, 宣焱, 杜淼, 刘玲, 吴惠文, 宋彬妤… - CHINESE JOURNAL …, 2022 - sxmufyc.edu.cn
… 摘要:SARSCoV2 是一种高致病性且传播迅速的病原体,通过刺突糖蛋白(… The impact
of mutations in SARSCoV2 spike on viral infectivity and antigenicity[J/OL]. Cell,2020,182(5): …

人類冠狀病毒229E 的宿主識別與抗原漂變之分子基礎

蔡淯璽 - 2023 - airitilibrary.com
… 急性呼吸綜合症冠狀病毒2型(SARS-CoV-2).相比之下,已經發現… suggested destabilizing
effects of the mutations, which were … consisting of two 229E spikes adopting an unprecedented …