过去一年中添加的文章,按日期排序

Immunogenicity of intranasal vaccine based on SARS-CoV-2 spike protein during primary and booster immunizations in mice

H Yang, Y Xie, S Li, C Bao, J Wang, C Li… - Human Vaccines & …, 2024 - Taylor & Francis
8 天前 - … of neutralizing antibodies against SARS-CoV-2 were evaluated through a
pseudovirus-based neutralization … tract infections caused by highly mutated SARS-CoV-2. We aim …

[HTML][HTML] Immunogenicity and protection efficacy of a COVID-19 DNA vaccine encoding spike protein with D614G mutation and optimization of large-scale DNA vaccine …

A Gül, S Erkunt Alak, H Can, M Karakavuk… - Scientific Reports, 2024 - nature.com
10 天前 - mutations in Turkey by sequencing the Spike gene in these samples. The sequence
of the SARS-CoV-2 … ELISA-based SARS-CoV-2 surrogate Virus Neutralization Test (sVNT) …

Impact of mutations in non-structural proteins on SARS-CoV-2 replication

EA Datsomor - 2024 - vtechworks.lib.vt.edu
11 天前 - … of the SARS-CoV-2 genome, notably within the spike protein, can impact transmission
… increased transmissibility and reduced neutralization by antibodies. Understanding the …

SARS-CoV-2 変異株Spike に対する高親和性Nanobody の合理的デザインを指向した構造学的研究

山口桂史 - 日本結晶学会誌, 2024 - jstage.jst.go.jp
25 天前 - … has highly potent neutralizing activity against SARS-CoV-2 has … P17 bound to the
SARS-CoV-2 receptor binding domain(… Furthermore, we identified mutations that decrease the …

Recurrent SARS-CoV-2 spike mutations confer growth advantages to select JN. 1 sublineages

Q Wang, IA Mellis, A Bowen, T Kowalski-Dobson… - bioRxiv, 2024 - biorxiv.org
26 天前 - mutations R346T, F456L, and T572I 211 confer a variety of phenotypic advantages
to SARS-CoV-2 … The SARS-CoV-2 594 neutralizing antibody response to SD1 and its …

[HTML][HTML] An unconventional VH1-2 antibody tolerates escape mutations and shows an antigenic hotspot on SARS-CoV-2 spike

B Liu, X Niu, Y Deng, Z Zhang, Y Wang, X Gao, H Liang… - Cell Reports, 2024 - cell.com
29 天前 - … syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein … the SARS-CoV-2 ancestral
strain, effectively neutralizes … overcome the effect of most Omicron mutations through its …

Characteristics of JN. 1-derived SARS-CoV-2 subvariants SLip, FLiRT, and KP. 2 in neutralization escape, infectivity and membrane fusion

P Li, JN Faraone, CC Hsu, M Chamblee, YM Zheng… - bioRxiv, 2024 - biorxiv.org
34 天前 - … To better understand the impact of spike mutations on these new variants, we
performed homology modeling 213 to investigate alterations in receptor engagement, …

Broad-spectrum RNA prophylactic and therapeutic interventions for SARS-CoV-2

A Gontu - 2024 - etda.libraries.psu.edu
41 天前 - … - one encoding the spike protein of SARS-CoV-2 and the … -neutralizing ability
across multiple SARS-CoV-2 variants … selection of mutations within the spike protein [145]. This …

Comprehensive Analysis of Omicron Subvariants: EG. 5 Rise, Vaccination Strategies, and Global Impact.

D Sil, S Gautam, S Saxena, S Joshi, D Kumar… - Current Drug …, 2024 - europepmc.org
47 天前 - … The emergence of new variants of the SARS-CoV-2 virus during the COVID-19
pandemic … with mutations like Q52H and F456L, contributing to its ability to bypass neutralizing

Antigenic Characterization of Circulating and Emerging SARS-CoV-2 Variants in the US throughout the Delta to Omicron Waves

H Di, EA Pusch, J Jones, NA Kovacs, N Hassell… - Vaccines, 2024 - mdpi.com
49 天前 - … The spike protein on the surface of the SARS-CoV-2 virion is the main target of the
human neutralizing … Delta, Mu and Omicron variants with additional spike mutations. Bars …