Transfection efficiency of chitosan vectors: effect of polymer molecular weight and degree of deacetylation

M Huang, CW Fong, E Khor, LY Lim - Journal of controlled release, 2005 - Elsevier
… to have higher transfection efficiency than high Mw (162 kDa) chitosan–DNA … efficiency
might be attributed to the rate of DNA dissociation from the chitosan vector as suggested by the

Kinetics and efficiency of chitosan reacetylation

M Lavertu, V Darras, MD Buschmann - Carbohydrate polymers, 2012 - Elsevier
… In this paper, we have characterized the kinetics and efficiency of chitosan reacetylation
in water–methanol mixtures of 0, 50 and 80% MeOH (v/v). A model and solution to …

In vitro gene delivery mediated by chitosan. Effect of pH, serum, and molecular mass of chitosan on the transfection efficiency

T Sato, T Ishii, Y Okahata - Biomaterials, 2001 - Elsevier
Chitosan largely enhanced the transfection efficiency of … Transfection efficiencies of the
pGL3/chitosan complexes were … : chitosan, serum, and molecular mass of chitosan. Transfection …

The effect of the degree of chitosan deacetylation on the efficiency of gene transfection

T Kiang, J Wen, HW Lim, KW Leong - Biomaterials, 2004 - Elsevier
… release of DNA, since it lowers the charge density, may increase steric … the degree of
chitosan deacetylation influences chitosan–DNA particle formation, DNA release, and the

Application of chitosan and chitosan derivatives as biomaterials

C Choi, JP Nam, JW Nah - Journal of Industrial and Engineering Chemistry, 2016 - Elsevier
… , the molecular weight (MW) of chitosan and the ionic strength of the solution influence the
solubility of chitosan. … efficiency than the high MW of chitosan, and the intranasal vaccination of …

Chitosan: A review of sources and preparation methods

SG Kou, LM Peters, MR Mucalo - International Journal of Biological …, 2021 - Elsevier
… As the precursor of chitosan, chitin is the most widely occurring biopolymer in nature after
cellulose: it can be found in a range of eukaryotic species such as crustacea, insects and fungi […

Quantitative evaluation of the antibacterial effectiveness and efficiency of chitosan considering the effect of neutralization

M Wang, S Bi, D Qin, C Su, H Wang, X Chen - Carbohydrate Polymers, 2021 - Elsevier
… Furthermore, the neutralizing ability of several metal ions was identified and the time
related antibacterial efficiency of chitosan was determined with the help of MgCl 2 neutralizer. …

[HTML][HTML] Evaluation of antibacterial efficiency of chitosan and chitosan nanoparticles on cariogenic streptococci: An in vitro study

A Aliasghari, MR Khorasgani, S Vaezifar… - Iranian journal of …, 2016 - ncbi.nlm.nih.gov
The results of this study supported the use of chitosan and … in a decrease in the zone of
growth inhibition. The lowest zones of inhibition by the chitosan and chitosan nanoparticle were …

Chitosan-DNA nanoparticles as non-viral vectors in gene therapy: strategies to improve transfection efficacy

S Mansouri, P Lavigne, K Corsi, M Benderdour… - European journal of …, 2004 - Elsevier
… In this study, the transfection efficiency of chitosan in HeLa cells in the presence of 10%
fetal calf serum was found comparable to that of another cationic polymer, polyethyleneimine (…

Chitosan–DNA complexes: Effect of molecular parameters on the efficiency of delivery

F Bordi, L Chronopoulou, C Palocci, F Bomboi… - Colloids and Surfaces A …, 2014 - Elsevier
… Here, in order to understand the relation between physicochemical and transfection
properties of Chitosan–DNA complexes, we study the efficiency of Chitosan–pDNA aggregates …