Abstract Background/Objectives The present article summarizes and analyzes the current
knowledge about the role of the epithelial to mesenchymal transition (EMT) in the systemic
invasiveness of pancreatic cancer. Method An electronic search of PubMed/MEDLINE,
EMBASE, and the Web of Science was used to identify relevant original articles and reviews.
Results The EMT represents a key step during normal embryogenesis. However, increasing
evidence reveals its essential role in the local progression and metastasis of pancreatic …