In vivo bioluminescent imaging (BLI) permits the visualization of engineered
bioluminescence from living cells and tissues to provide a unique perspective toward the
understanding of biological processes as they occur within the framework of an authentic in
vivo environment. The toolbox of in vivo BLI includes an inventory of luciferase compounds
capable of generating bioluminescent light signals along with sophisticated and powerful
instrumentation designed to detect and quantify these light signals non-invasively as they …