The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-regulated kinase (ERK) …

C Cai, L Teng, D Vu, JQ He, Y Guo, Q Li… - Journal of Biological …, 2012 - ASBMB
Intracoronary delivery of c-kit-positive human cardiac stem cells (hCSCs) is a promising
approach to repair the infarcted heart, but it is severely limited by the poor survival of donor
cells. Cobalt protoporphyrin (CoPP), a well known heme oxygenase 1 inducer, has been
used to promote endogenous CO generation and protect against ischemia/reperfusion
injury. Therefore, we determined whether preconditioning hCSCs with CoPP promotes CSC
survival. c-kit-positive, lineage-negative hCSCs were isolated from human heart biopsies …

Correction: The heme oxygenase 1 inducer (CoPP) protects human cardiac stem cells against apoptosis through activation of the extracellular signal-related kinase …

C Cai, L Teng, D Vu, JQ He, Y Guo, Q Li… - Journal of Biological …, 2019 - ASBMB
The wrong tubulin immunoblot was used in Fig. 1 E. The wrong FACS plot image was used
in the lower right panel of Fig. 5 C. The wrong t-ERK and tubulin immunoblots were used in
Fig. 7 C. In supplemental Fig. S2 B, the wrong tubulin immunoblot was used. Additionally,
the wrong number (n 4) of independent experiments was used for the FACS analyses shown
in Figs. 2, B and C, 3, C and D, 4, C and D, and 5, C and D. The FACS analyses for cell
apoptosis assays were performed at the same time for hCSCs expressing scramble shRNA …
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