This study aims to investigate the impact of education and training, work discipline and organizational culture on employee’s performance. The study is conducted at the Disaster Management and Fire Department Office in Palembang City, Indonesia. There are seven offices of disaster management and fire department officials in all over Palembang city and the total population is 360 firefighters. The sample size is 154 respondents that are taken proportionately from each office. A survey research using questionnaire is employed to collect the data. The variables are education and training (X1), work discipline (X2), organizational culture (X3) and employees’ performance (Y). Technology and labor force changes, service and performance improvement and rules’ adjustment are indicators for education and training. Remuneration, supervision, and firmness are indicators for work discipline. Innovation, people oriented and composure are indicators for organizational culture. Working standard, work equipment and tool and work opportunity are indicators for employees’ performance. A regression equation model is employed. The result reveals that there is a positive and significant effect of education and training, work discipline and organizational culture on employee’s performance.