The importance of Zebrafish in biomedical research
B Tavares, SS Lopes - Acta medica portuguesa, 2013 - actamedicaportuguesa.com
B Tavares, SS Lopes
Acta medica portuguesa, 2013•actamedicaportuguesa.comAbstract Introduction: Zebrafish (Danio rerio) is an ideal model organism for the study of
vertebrate development. This is due to the large clutches that each couple produces, with up
to 200 embryos every 7 days, and to the fact that the embryos and larvae are small,
transparent and undergo rapid external development. Material and Methods: Using scientific
literature research tools available online and the keywords Zebrafish, biomedical research,
human disease, and drug screening, we reviewed original studies and reviews indexed in …
vertebrate development. This is due to the large clutches that each couple produces, with up
to 200 embryos every 7 days, and to the fact that the embryos and larvae are small,
transparent and undergo rapid external development. Material and Methods: Using scientific
literature research tools available online and the keywords Zebrafish, biomedical research,
human disease, and drug screening, we reviewed original studies and reviews indexed in …
Abstract
Introduction: Zebrafish (Danio rerio) is an ideal model organism for the study of vertebrate development. This is due to the large clutches that each couple produces, with up to 200 embryos every 7 days, and to the fact that the embryos and larvae are small, transparent and undergo rapid external development.
Material and Methods: Using scientific literature research tools available online and the keywords Zebrafish, biomedical research, human disease, and drug screening, we reviewed original studies and reviews indexed in PubMed.
Results: In this review we summarized work conducted with this model for the advancement of our knowledge related to several human diseases. We also focused on the biomedical research being performed in Portugal with the zebrafish model.
Discussion: Powerful live imaging and genetic tools are currently available for zebrafish making it a valuable model in biomedical
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