Extracellular vesicles (EVs) are key mediators of intercellular communication that have been
ignored for decades. Tumour cells benefit from the secretion of vesicles as they can
influence the behaviour of neighbouring tumour cells within the tumour microenvironment.
Several studies have shown that extracellular vesicles play an active role in pre-metastatic
niche formation and importantly, they are involved in the metastatic organotropism of
different tumour types. Tumour-derived EVs carry and transfer molecules to recipient cells …