Sjögren's syndrome is a chronic autoimmune disorder, characterized by lymphocytic
infiltration and malfunction of the exocrine glands, resulting in dry mouth and eyes. The
syndrome can present either alone (primary Sjögren's syndrome) or in the context of an
underlying connective tissue disease (secondary Sjögren's syndrome). Systemic features,
resulting from cutaneous, respiratory, renal, hepatic, neurologic, and vascular involvement,
often occur. Two types of primary Sjögren's syndrome are currently recognized: a benign …

The guideline will be developed using the methods and processes outlined in Creating
Clinical Guidelines: Our Protocol. This development process to produce guidance, advice
and recommendations for practice has National Institute for Health and Care Excellence
(NICE) accreditation.