The molecular mechanism of nuclear signaling for degradation of cytoplasmic DNA: Importance in DNA damage response and cancer
This review summarizes and addresses non-coding RNAs (rRNA, tRNA, Vault and Y RNA,
snRNA, and miRNA) cytoplasmic decay pathways, the molecules, enzymes, and
modifications such as uridylation, which play vital roles in the degradation processes in
various eukaryotic organisms. Plus, SIRT1′ s role in fundamental cellular processes,
including autophagy, DNA repair, DNA damage response (DDR), and the molecular
mechanisms, is explored. Further, the HuR (an RNA-binding protein) impact on the …
snRNA, and miRNA) cytoplasmic decay pathways, the molecules, enzymes, and
modifications such as uridylation, which play vital roles in the degradation processes in
various eukaryotic organisms. Plus, SIRT1′ s role in fundamental cellular processes,
including autophagy, DNA repair, DNA damage response (DDR), and the molecular
mechanisms, is explored. Further, the HuR (an RNA-binding protein) impact on the …
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