The physics of protein self-assembly

JJ McManus, P Charbonneau, E Zaccarelli… - Current opinion in colloid …, 2016 - Elsevier
Understanding protein self-assembly is important for many biological and industrial
processes. Proteins can self-assemble into crystals, filaments, gels, and other amorphous
aggregates. The final forms include virus capsids and condensed phases associated with
diseases such as amyloid fibrils. Although seemingly different, these assemblies all
originate from fundamental protein interactions and are driven by similar thermodynamic
and kinetic factors. Here we review recent advances in understanding protein self-assembly …
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