The thermotropism and prototropism of ternary mixtures of ceramide C16, cholesterol and palmitic acid. An exploratory study

SL Souza, J Valério, SS Funari, E Melo - Chemistry and physics of lipids, 2011 - Elsevier
Mixtures of ceramides with other lipids in the presence of water are key components of the
structure of the lipid matrix of the stratum corneum and are involved in lateral phase
separation processes occurring in lipid membranes. Besides their structural role, ceramides
are functional for cell signaling and trafficking. We elected, as our object of study, a mixture
of N-hexadecanoylceroyl-d-erythro-sphyngosine, C16-Cer, with cholesterol, Ch, in a molar
proportion 54: 46 in excess water to which palmitic acid, PA, is added in varying amounts …
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