Background. Variations in the timing of dialysis initiation may explain some geographical
variations in renal replacement therapy (RRT) incidence, but this effect has never been
quantified. Methods. Using data from the French Renal Epidemiology and Information
Network registry, we quantified the association between RRT incidence in 2006–07 and
median estimated glomerular filtration rate (eGFR) values before starting dialysis at the
administrative district level with geographically appropriate methods. Results. Crude RRT …

… cover image: The timing of dialysis initiation affects the incidence of renal replacement
therapy.: … The impact of increased eGFR at initiation should be taken into account in
guidelines recommending earlier dialysis start. … The timing of dialysis initiation affects the
incidence of renal replacement therapy.: …