… to other putative T cell epitopes. JanusMatrix defines cross-reactive T cell epitopes as those
that … We expect that the exploration of the two-faced T cell epitope using JanusMatrix will …

… We have examined TCR-facing residues for conservation against a … JanusMatrix, we
discovered a promiscuous class II epitope … Finally, we are exploring means to fine-tune the epitope …

… JanusMatrix Delta values for the peptides used in this study ranged from 0 to 37.89. A … The
two-faced T cell epitope: examining the host-microbe interface with JanusMatrix. Hum Vaccin …

… examine T cell epitopes and their role in vaccines, using the power of immunoinformatics. …
Measure) as well as an adaptation of JanusMatrix to iTEM (J-iTEM), we found T cell responses …

… To define cross-conserved T cell epitopes, we use JanusMatrix, which operates in conjunction
with an existing T cell epitope-… The two-faced T cell epitope: examining the host-microbe …

… JanusMatrix score for each protein was determined using the average JanusMatrix score for
all the putative class II epitopes … In the current study we decided to verify immunogenicity of …

… Using JanusMatrix, we identified human-like T-cell epitopes in the genomes of viruses
and bacteria. Analyzing pathogens that co-evolved with humans (eg EBV, CMV, HIV), we …

… epitope databases, Moise et al. identified a JanusMatrix score threshold of three, as defining
potentially tolerated epitope (46), while T cell epitopes with JanusMatrix … for this study are …

… JanusMatrix algorithm to identify epitopes that may be unlikely to stimulate effector T cell
responses due to similarity (at the T cell … T cell epitope clusters in the seven proteins under study…

… To define cross-conserved T cell epitopes, we use JanusMatrix… T cell epitope-mapping
platform (EpiMatrix)31 JanusMatrix … The two-faced T cell epitope: Examining the host-microbe …