is critical to the function of excitable tissues such as the heart and brain. Disruptions to C× 43
GJ organization are thought to be a factor in cardiac arrhythmias and are also implicated in
epilepsy. This article is based on a presentation to the 4th Larry and Horti Fairberg
Workshop on Interactive and Integrative Cardiology and summarizes the work of Gourdie
and his lab on C× 43 GJs in the heart. Background and perspective of recently published …