[PDF][PDF] The use of vancomycin with its therapeutic and adverse effects: a review.
FR Bruniera, FM Ferreira, LRM Saviolli… - European Review for …, 2015 - europeanreview.org
European Review for Medical & Pharmacological Sciences, 2015•europeanreview.org
RESULTS: The main adverse effects of vancomycin are: hypotension, phlebitis,
nephrotoxicity, ototoxicity, hypersensitivity reactions, red man syndrome, neutropenia, chills,
fever, interstitial nephritis. CONCLUSIONS: The use of vancomycin is still very common;
however, inadequate doses and prolonged therapy pose a risk of increasing minimum
inhibitory concentrations (MICs), resulting in subtherapeutic levels, treatment failures and
toxicity. Therefore, further studies should be conducted to optimize the administration of …
nephrotoxicity, ototoxicity, hypersensitivity reactions, red man syndrome, neutropenia, chills,
fever, interstitial nephritis. CONCLUSIONS: The use of vancomycin is still very common;
however, inadequate doses and prolonged therapy pose a risk of increasing minimum
inhibitory concentrations (MICs), resulting in subtherapeutic levels, treatment failures and
toxicity. Therefore, further studies should be conducted to optimize the administration of …
RESULTS: The main adverse effects of vancomycin are: hypotension, phlebitis, nephrotoxicity, ototoxicity, hypersensitivity reactions, red man syndrome, neutropenia, chills, fever, interstitial nephritis.
CONCLUSIONS: The use of vancomycin is still very common; however, inadequate doses and prolonged therapy pose a risk of increasing minimum inhibitory concentrations (MICs), resulting in subtherapeutic levels, treatment failures and toxicity. Therefore, further studies should be conducted to optimize the administration of vancomycin, monitoring treatments from the beginning in order to ensure a safe and effective use of the drug.
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