The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare
S El Bardai, N Morel, M Wibo, N Fabre… - Planta …, 2003 - thieme-connect.com
S El Bardai, N Morel, M Wibo, N Fabre, G Llabres, B Lyoussi, J Quetin-Leclercq
Planta medica, 2003•thieme-connect.comCrude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of
KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and
chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin
as the most active compounds.
KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and
chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin
as the most active compounds.
Abstract
Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.
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