Purpose: At the present time the role of stem cells and its therapeutic effects is well known.
Human or animal (bone marrow or cord blood) stem cells in stem cell therapy are a
promising attempt to improve the recovery after post embryonic injuries. Materials and
Methods: The present study was carried out on young Wistar rats. At first, cord blood stem
cells (CBSCs) were isolated, and labeled with Bromodeoxyuridine (BRDU). Animals were
subjected to internal carotid artery occlusion (lCA) for 20 minutes. After that, 2xl0 5 isolated …

BACKGROUND AND OBJECTIVE: Human umbilical cord blood (HUCB) is a rich source of
stem cells. The aim of this study was the investigation of the therapeutic effects of these cells
on cerebral ischemia in rat. METHODS: This study was carried out on 30 male Wistar rats
(100-150 g). They were divided into three groups. Firstly, to create a laboratory model of
ischemic stroke, right carotid artery of animals was occluded for 30 minutes in two groups of
experimental and sham. Then, mononuclear cells of cord blood were isolated and labeled …