Single nucleotide polymorphisms tumor necrosis factor (TNF) G-308A, coagulation factors V
G1691A and II G20210A, methylenetetrahydrofolate reductase (MTHFR) C677T, as well as
the angiotensin-converting enzyme (ACE) insertion/deletion polymorphism were
investigated in 86 women with a history of premature delivery (PD) and compared with those
of a control group of adults from Guadalajara, Mexico (a minimum of 162 individuals were
typed for each polymorphism). Significant differences in the frequency of these …