Importance Low-molecular-weight heparin is recommended over warfarin for the treatment
of acute venous thromboembolism (VTE) in patients with active cancer largely based on
results of a single, large trial. Objective To study the efficacy and safety of tinzaparin vs
warfarin for treatment of acute, symptomatic VTE in patients with active cancer. Design,
Settings, and Participants A randomized, open-label study with blinded central adjudication
of study outcomes enrolled patients in 164 centers in Asia, Africa, Europe, and North …