Pluronic F-127 gel is used as vehicle for various topical applications. In the present study,
effects of topical application of pluronic F-127 gel were evaluated in cutaneous wound
healing in Wistar rats. Normal saline solution and pluronic F-127 gel (25%) were applied
topically on open excision wounds for 14 days. Photography, determination of percentage
wound contraction, and collection of granulation tissue were done on days 3, 7, 11 and 14
post-wounding. Topical application of gel (once daily) significantly increased the wound …