… in the preparation of pamamycin-607 (1). The acid A may be obtained from the ester D,
employing the key radical cyclization reaction 5 converting the β-alkoxyvinyl ketone C into the …

… Although 4a was subsequently used to complete the total synthesis of pamamycin-607 (1a),
the preparation of aldol adducts 4b and 4c—precursors of pamamycin-621D (1b) and …

… the most prominent member pamamycin-607, could be extended … access to pamamycin-607
and disclosed the preparation of … Whereas during the synthesis of pamamycin-607, we had …

… pamamycin-607[9] and in this paper we report an extension of our methodology to the
synthesis … One advantage of this stratPamamycin-607 possesses a remarkable range of chemi- …

… We now describe total syntheses of pamamycin 607 1 and the methyl ester of nonactic
acid 2. Our approach is based on the stereoselective cyclisation, to 2,5-cis-disubstituted …

… synthesis of (+)-methyl nonactate) 1 We decided to demonstrate the versatility of our method
by the total synthesis of pamamycin-607 … This article describes the synthesis of the southern …

… We have recently accomplished a total synthesis of pamamycin-607 (1 a) 4 , 5 by
extensive application of sultone methodology. To facilitate more detailed studies of structure–activity …

… 1a More recent investigations on the antimycobacterial activity of pamamycin-607 (1 a) on
25 independent M. tuberculosis clinical isolates (either susceptible, mono-, or multiresistant to …

… To our disappointment, only 2-epi-pamamycin-607 (11) 11 and 2,2′-bisepi-pamamycin-607
(12) 12 were isolated in 28 and 17% yields, respectively, after mixed anhydride activation …

… ) - C(18) of pamamycin 607 was synthesised by another member … and completed the first
total synthesis of pamamycin-607 (1). … , no total synthesis of pamamycin-607 had been reported. …