Transcriptional Profile of Mycobacterium tuberculosis in an in vitro Model of Intraocular Tuberculosis
S Abhishek, UN Saikia, A Gupta, R Bansal… - Frontiers in cellular …, 2018 - frontiersin.org
Background: Intraocular tuberculosis (IOTB), an extrapulmonary manifestation of
tuberculosis of the eye, has unique and varied clinical presentations with poorly understood
pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in
TB endemic countries, it is essential to study the pathogenesis of IOTB. Clinical and
histopathologic studies suggest the presence of Mycobacterium tuberculosis in retinal
pigment epithelium (RPE) cells. Methods: A human retinal pigment epithelium (ARPE-19) …
tuberculosis of the eye, has unique and varied clinical presentations with poorly understood
pathogenesis. As it is a significant cause of inflammation and visual morbidity, particularly in
TB endemic countries, it is essential to study the pathogenesis of IOTB. Clinical and
histopathologic studies suggest the presence of Mycobacterium tuberculosis in retinal
pigment epithelium (RPE) cells. Methods: A human retinal pigment epithelium (ARPE-19) …
[引用][C] Transcriptional profile of Mycobacterium tuberculosis in an in vitro model of intraocular tuberculosis. Front Cell Infect Microbiol 8: 330
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