Transcriptomic Analysis of Circulating Leukocytes Obtained during the Recovery from Clinical Mastitis Caused by Escherichia coli in Holstein Dairy Cows
Simple Summary Escherichia coli is a bacterium which infects cow udders causing clinical
mastitis, a potentially severe disease with welfare and economic consequences. During an
infection, white blood cells (leukocytes) enter the udder to provide immune defence and
assist tissue repair. We sequenced RNA derived from circulating leukocytes to investigate
which genes are up-or down-regulated in dairy cows with naturally occurring cases of
clinical mastitis in comparison with healthy control cows from the same farm. We also looked …
mastitis, a potentially severe disease with welfare and economic consequences. During an
infection, white blood cells (leukocytes) enter the udder to provide immune defence and
assist tissue repair. We sequenced RNA derived from circulating leukocytes to investigate
which genes are up-or down-regulated in dairy cows with naturally occurring cases of
clinical mastitis in comparison with healthy control cows from the same farm. We also looked …