Trends in antipsychotic use in dementia 1999-2007

HC Kales, K Zivin, HM Kim, M Valenstein… - Archives of general …, 2011 - jamanetwork.com
Context Use of atypical antipsychotics for neuropsychiatric symptoms of dementia increased
markedly in the 1990s. Concerns about their use began to emerge in 2002, and in 2005, the
US Food and Drug Administration warned that use of atypical antipsychotics in dementia
was associated with increased mortality. Objective To examine changes in atypical and
conventional antipsychotic use in outpatients with dementia from 1999 through 2007.
Design Time-series analyses estimated the effect of the various warnings on atypical and …
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