Triglyceride levels as a risk factor during pregnancy; biological modeling; systematic review

AC MJ, SL AM - Nutrición Hospitalaria, 2015 - europepmc.org
AC MJ, SL AM
Nutrición Hospitalaria, 2015europepmc.org
Objective the objective of this review is to analyze the studies that have investigated
triglyceride levels during pregnancy as a risk factor for cardiovascular disease in the last
weeks of pregnancy and childbirth. Methods a systematic search was made and 14 specific
articles on the subject were selected following the PRISMA guidelines. Results in normal
pregnancy decreased the level of lipids in the first weeks, followed by a gradual increase.
Especially high from the 12th week of gestation. This increase in plasma levels of circulating …
Objective
the objective of this review is to analyze the studies that have investigated triglyceride levels during pregnancy as a risk factor for cardiovascular disease in the last weeks of pregnancy and childbirth.
Methods
a systematic search was made and 14 specific articles on the subject were selected following the PRISMA guidelines.
Results
in normal pregnancy decreased the level of lipids in the first weeks, followed by a gradual increase. Especially high from the 12th week of gestation. This increase in plasma levels of circulating lipids occurs linearly, reaching a peak a few days before delivery. This increase results because of the increased estrogen levels and insulin resistance. It has also been associated with prolactin levels.
Conclusions
through this review, it has been able to demonstrate the relationship of elevated triglycerides some pathologies or more frequent changes in risk pregnancies, in which a significantly higher elevation occurs compared to normal pregnancies. It is in this context that the biological modeling may be particularly important, facilitating the creation of models and percentile curves applicable to the population, and allow monitoring of changes in triglycerides, which end up pointing situations passing be predictors of a potentially pathological situation. Thus, appropriate interventions would be carried rafter more briefly, and see so favored adequate primary prevention.
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