Tuberculariols A – C, New Sesquiterpenes from the Mutant Strain M‐741 of Tubercularia sp. TF5

R Xu, MZ Wang, CH Lu, ZH Zheng… - Helvetica Chimica …, 2009 - Wiley Online Library
R Xu, MZ Wang, CH Lu, ZH Zheng, YM Shen
Helvetica Chimica Acta, 2009Wiley Online Library
Three new sesquiterpenes, tuberculariols A–C (1–3, resp.), were isolated from the mutant
strain M‐741 of Tubercularia sp. TF5, an endophytic fungus of Taxus mairei. Their structures
were elucidated by spectroscopic analyses including 1D‐and 2D‐NMR experiments, and
HR‐Q‐TOF‐MS. Antitumor and antibacterial properties of these compounds were evaluated.
Abstract
Three new sesquiterpenes, tuberculariols A–C (13, resp.), were isolated from the mutant strain M‐741 of Tubercularia sp. TF5, an endophytic fungus of Taxus mairei. Their structures were elucidated by spectroscopic analyses including 1D‐ and 2D‐NMR experiments, and HR‐Q‐TOF‐MS. Antitumor and antibacterial properties of these compounds were evaluated.
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