Tumor programmed cell death ligand 1 expression correlates with nodal metastasis in patients with cutaneous squamous cell carcinoma of the head and neck
JM García-Pedrero, P Martínez-Camblor… - Journal of the American …, 2017 - Elsevier
Background Binding of tumor-expressed programmed cell death ligand 1 (PD-L1) to the
programmed cell death 1 (PD-1) surface receptor blocks T-cell activation thereby leading to
immune evasion. Tumor PD-L1 expression has been associated with poor outcome in a
wide variety of cancers; however, data in cutaneous squamous cell carcinoma (cSCC) are
scarce and conflicting. Objective To investigate the relationship of tumor PD-L1 expression
with the clinicopathologic features and prognosis of cSCC. Methods PD-L1 expression was …
programmed cell death 1 (PD-1) surface receptor blocks T-cell activation thereby leading to
immune evasion. Tumor PD-L1 expression has been associated with poor outcome in a
wide variety of cancers; however, data in cutaneous squamous cell carcinoma (cSCC) are
scarce and conflicting. Objective To investigate the relationship of tumor PD-L1 expression
with the clinicopathologic features and prognosis of cSCC. Methods PD-L1 expression was …
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