Two weeks of single-leg immobilization alters intramyocellular lipid storage characteristics in healthy, young women
MN Black, JA Wilkinson, EK Webb… - Journal of Applied …, 2021 - journals.physiology.org
Muscle disuse rapidly induces insulin resistance (IR). Despite a relationship between
intramyocellular lipid (IMCL) content and IR, during muscle-disuse IR develops before IMCL
accumulation, suggesting that IMCL are not related to disuse-induced IR. However, recent
studies show that it is not total IMCL content, but IMCL size and location that are related to
IR. Changes in these IMCL parameters may occur prior to increases in IMCL content, thus
contributing to disuse-induced IR. Omega-3 fatty acids may mitigate the effects of disuse on …
intramyocellular lipid (IMCL) content and IR, during muscle-disuse IR develops before IMCL
accumulation, suggesting that IMCL are not related to disuse-induced IR. However, recent
studies show that it is not total IMCL content, but IMCL size and location that are related to
IR. Changes in these IMCL parameters may occur prior to increases in IMCL content, thus
contributing to disuse-induced IR. Omega-3 fatty acids may mitigate the effects of disuse on …
Two-weeks of single-leg immobilization alters intramyocellular lipid storage characteristics in healthy, young 1 women. 2 3 Merryl N Black1, Jennifer A Wilkinson1 …
SM McGlory, MC Devries, M Devries-Aboud - journals.physiology.org
ABSTRACT 48 Muscle disuse rapidly induces insulin resistance (IR). Despite a relationship
between intramyocellular lipid 49 (IMCL) content and IR, during muscle-disuse IR develops
before IMCL accumulation, suggesting that IMCL 50 are not related to disuse-induced IR.
However, recent studies show that it is not total IMCL content, but IMCL 51 size and location
that are related to IR. Changes in these IMCL parameters may occur prior to increases in 52
IMCL content, thus contributing to disuse-induced IR. Omega-3 fatty acids may mitigate the …
between intramyocellular lipid 49 (IMCL) content and IR, during muscle-disuse IR develops
before IMCL accumulation, suggesting that IMCL 50 are not related to disuse-induced IR.
However, recent studies show that it is not total IMCL content, but IMCL 51 size and location
that are related to IR. Changes in these IMCL parameters may occur prior to increases in 52
IMCL content, thus contributing to disuse-induced IR. Omega-3 fatty acids may mitigate the …
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