Ultra-Cold Cryogenic TEM with Liquid Helium and High Stability
arXiv preprint arXiv:2402.00636, 2024•arxiv.org
Cryogenic transmission electron microscopy has revolutionized structural biology and
materials science, but achieving temperatures below the boiling point of liquid nitrogen
remains a long-standing aspiration. We introduce an ultra-cold liquid helium transmission
electron microscope specimen holder, featuring continuous cryogen flow and vibration
decoupling. This instrument is compatible with modern aberration-corrected microscopes
and achieves sub-25 K base temperature, ${\pm} $2 mK thermal stability over many hours …
materials science, but achieving temperatures below the boiling point of liquid nitrogen
remains a long-standing aspiration. We introduce an ultra-cold liquid helium transmission
electron microscope specimen holder, featuring continuous cryogen flow and vibration
decoupling. This instrument is compatible with modern aberration-corrected microscopes
and achieves sub-25 K base temperature, ${\pm} $2 mK thermal stability over many hours …
Cryogenic transmission electron microscopy has revolutionized structural biology and materials science, but achieving temperatures below the boiling point of liquid nitrogen remains a long-standing aspiration. We introduce an ultra-cold liquid helium transmission electron microscope specimen holder, featuring continuous cryogen flow and vibration decoupling. This instrument is compatible with modern aberration-corrected microscopes and achieves sub-25 K base temperature, 2 mK thermal stability over many hours, and atomic resolution--setting the stage for a new era of cryogenic electron microscopy.
arxiv.org
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