Ultra high-field (7tesla) magnetic resonance spectroscopy in Amyotrophic Lateral Sclerosis
… (Cho), a marker of cell membrane turnover; myo-inositol (mI) a marker of glial activation,
and … Here, we used 7 Tesla MRS to quantify brain metabolites and correlate them with ALS …
and … Here, we used 7 Tesla MRS to quantify brain metabolites and correlate them with ALS …
[HTML][HTML] Emerging methods and applications of ultra-high field MR spectroscopic imaging in the human brain
… Magnetic Resonance Spectroscopic Imaging (MRSI) of the … in diseases such as tumors,
multiple sclerosis, epilepsy, or … from myo-Inositol, which are difficult to quantify at lower field …
multiple sclerosis, epilepsy, or … from myo-Inositol, which are difficult to quantify at lower field …
Ultrahigh-field MRI: where it really makes a difference
… In multiple sclerosis (MS), 7‑T imaging enables visualization … MR spectroscopic imaging in
clinically reasonable scan … damage and an increase of myo-Inositol (mIns) from gliosis and …
clinically reasonable scan … damage and an increase of myo-Inositol (mIns) from gliosis and …
Ultra-high-field MR imaging in multiple sclerosis
… The increased availability of ultra-high-field magnets (7 Tesla … resonance spectroscopy
(MRS) at ultra-high-field has … choline, as well as many other metabolites (ie, myo-inositol …
(MRS) at ultra-high-field has … choline, as well as many other metabolites (ie, myo-inositol …
Multinuclear magnetic resonance spectroscopy at ultra-high-field: assessing human cerebral metabolism in healthy and diseased states
P Veeraiah, JFA Jansen - Metabolites, 2023 - mdpi.com
… Multiple sclerosis (MS) is an autoimmune neurodegenerative disease which mainly
involves neuroinflammation and demyelination. Although reduced tNAA has been consistently …
involves neuroinflammation and demyelination. Although reduced tNAA has been consistently …
[HTML][HTML] An In-vivo 1H-MRS short-echo time technique at 7T: Quantification of metabolites in chronic multiple sclerosis and neuromyelitis optica brain lesions and …
… We used an ultra-high field (7T) scanner, to allow separation … We wished to test the hypotheses
that (1) myo-Inositol would … Resonance Spectroscopy (MRS) data using a seven tesla (7T…
that (1) myo-Inositol would … Resonance Spectroscopy (MRS) data using a seven tesla (7T…
Linking cortical lesions to metabolic changes in multiple sclerosis using 7T proton MR spectroscopy
… volume and regional NAA and myo-inositol levels. Here, we … Leveraging the improved
sensitivity of ultra-high field MRI for … of cortical lesions in multiple sclerosis. We provide evidence …
sensitivity of ultra-high field MRI for … of cortical lesions in multiple sclerosis. We provide evidence …
1-H MRSI in patients with relapsing multiple sclerosis at 7 Tesla (P6. 121)
… Background: Ultra high-field MR spectroscopic imaging potentially provides mechanistic
insights in MS. With improved detection of myo-Inositol (mI), glutamate (Glu), glutathione (GSH), …
insights in MS. With improved detection of myo-Inositol (mI), glutamate (Glu), glutathione (GSH), …
An optimal 1H-MRS technique at 7T: Proof-of-principle in Chronic Multiple Sclerosis and Neuromyelitis Optica Brain Lesions and Normal Appearing Brain Tissue
… Magnetic Resonance Spectroscopy (MRS) allows for the non-… pathologically distinct diseases,
multiple sclerosis (MS) and … We used an ultra-high field (7T) scanner, to allow separation …
multiple sclerosis (MS) and … We used an ultra-high field (7T) scanner, to allow separation …
Ultra-high field proton MR spectroscopy in early-stage amyotrophic lateral sclerosis
I Cheong, M Marjańska, DK Deelchand… - Neurochemical …, 2017 - Springer
… Myo-inositol levels in the motor cortex were significantly higher in subjects with probable
ALS than in controls (p = 0.02). Finally, Glu levels in subjects with either probable or definite …
ALS than in controls (p = 0.02). Finally, Glu levels in subjects with either probable or definite …