Ultra-high-performance liquid chromatography–tandem mass spectrometry for determining the presence of eleven personal care products in surface and wastewaters

M Pedrouzo, F Borrull, RM Marcé, E Pocurull - Journal of Chromatography …, 2009 - Elsevier
Journal of Chromatography A, 2009Elsevier
Personal care products (PCPs) are widely used emerging contaminants which can cause
adverse environmental effects. This paper reports the development and validation of a
method based on solid-phase extraction (SPE) and ultra-high-performance liquid
chromatography–electrospray ionisation–tandem mass spectrometry (UHPLC–(ESI) MS–
MS) for simultaneously determining eleven PCPs: 4 preservatives (methylparaben;
ethylparaben; benzylparaben; propylparaben); 2 antimicrobial agents (triclocarban and …
Personal care products (PCPs) are widely used emerging contaminants which can cause adverse environmental effects. This paper reports the development and validation of a method based on solid-phase extraction (SPE) and ultra-high-performance liquid chromatography–electrospray ionisation–tandem mass spectrometry (UHPLC–(ESI)MS–MS) for simultaneously determining eleven PCPs: 4 preservatives (methylparaben; ethylparaben; benzylparaben; propylparaben); 2 antimicrobial agents (triclocarban and triclosan) and 5 UV filters (2,4-dihydroxybenzophenone; 2,2-dihydroxy-4-methoxybenzophenone; benzophenone-3; octocrylene and octyldimethyl-p-aminobenzoic acid) in environmental waters in only 9 run minutes of chromatographic separation. The SPE was carried out with two polymeric cartridges (Oasis HLB and Bond Elut Plexa). The recoveries obtained with Bond Elut Plexa were between 69% and 101% for 500mL of river waters, with the exception of octyldimethyl-p-aminobenzoic acid (46%). Limits of detection for 500mL of river water were in the range of 1–5ng/L. Oasis HLB was chosen for wastewater samples with recoveries between 38% and 92% (250mL of effluents) and 36–89% (100mL of influents). In both wastewater samples, octyldimethyl-p-aminobenzoic acid and methylparaben showed the lowest recoveries (20% and 27%). The method revealed benzophenone-3 as having the highest concentration levels (7ng/L) in river waters. Most of PCPs determined were found in influent waters being methylparaben and propylparaben the ones found at highest concentration with values of 5613 and 1945ng/L, respectively. In effluent waters, significant lower levels of some PCPs were found, being benzophenone-3 the one found at the highest concentration (100ng/L).
Elsevier
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