I Lavon, J Kost - Drug discovery today, 2004 - Elsevier
… Tachibana [41, 55] reported that the use of low-frequency ultrasound (48 kHz) enhanced transdermaltransport of insulin across diabetic rat skin. Merino et al. [18] compared the …
BCQ Seah, BM Teo - International journal of nanomedicine, 2018 - Taylor & Francis
… ultrasound to validate that the previously ascertained results were applicable to transdermal transport. … that dual-frequency SP enhanced the percutaneous transport of glucose ( Figure …
… However, we found that 1 MHz ultrasoundenhanced estradiol transdermaltransport by a factor of 13, whereas 3 MHz ultrasoundenhancedtransport only by 50% (compare cases 1 …
G Merino, YN Kalia, MB Delgado-Charro… - Journal of Controlled …, 2003 - Elsevier
… The aims of this work were: (i) to examine the role of ultrasound (US) frequency and intensity on the transport of glucose and mannitol across porcine skin in vitro, (ii) to quantify the …
… the mechanisms of ultrasound-permeability enhancement, and … of ultrasound are discussed. It is stressed that developing … for the purpose of visualizing the localized transport regions. …
ME Johnson, S Mitragotri, A Patel… - Journal of …, 1996 - Elsevier
… chemical enhancers and ultrasound can each individually increase transdermal drug transport, we … and ultrasound may result in a greater enhancement than that resulting from each …
… The authors theorized that the enhancedtransdermaltransport in the course of low-frequency ultrasound application occurs through the keratinocytes rather than the hair follicles. They …
S Mitragotri, J Farrell, H Tang, T Terahara, J Kost… - Journal of controlled …, 2000 - Elsevier
… Hence we study the dependence of transdermaltransportenhancement as well as cavitation on ultrasound parameters including intensity, duty cycle and exposure time. …
… a transdermal delivery … enhancement from drug to drug. This paper also presents an equation to qualitatively predict whether therapeutic ultrasound may enhance transdermaltransport …