The Notch pathway plays a key role in differentiation, proliferation, and influencing cell fate
decision in multiple organisms and tissues including the epidermis and its appendages. The
role of Notch-1 in psoriasis has not been widely evaluated; therefore, the current study
aimed to evaluate its role in etiopathogenesis of this common skin disease. The current
study used immunohistochemical technique to evaluate Notch-1 expression in 35 lesional
biopsies of patients having chronic plaque psoriasis in comparison with normal skin …