Urinary biomarkers and renal recovery in critically ill patients with renal support
N Srisawat, X Wen, MJ Lee, L Kong… - Clinical Journal of the …, 2011 - journals.lww.com
Results We defined renal recovery as alive and free of dialysis at 60 days from the start of
RRT. Patients who recovered had higher uCystatin C on day 1 (7.27 versus 6.60 ng/mg·
creatinine) and lower uHGF on days 7 and 14 (2.97 versus 3.48 ng/mg· creatinine; 2.24
versus 3.40 ng/mg· creatinine). For predicting recovery, decreasing uNGAL and uHGF in the
first 14 days was associated with greater odds of renal recovery. The most predictive model
combined relative changes in biomarkers with clinical variables and resulted in an area …
RRT. Patients who recovered had higher uCystatin C on day 1 (7.27 versus 6.60 ng/mg·
creatinine) and lower uHGF on days 7 and 14 (2.97 versus 3.48 ng/mg· creatinine; 2.24
versus 3.40 ng/mg· creatinine). For predicting recovery, decreasing uNGAL and uHGF in the
first 14 days was associated with greater odds of renal recovery. The most predictive model
combined relative changes in biomarkers with clinical variables and resulted in an area …
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