Urinary single-cell profiling captures the cellular diversity of the kidney

A Abedini, YO Zhu, S Chatterjee, G Halasz… - Journal of the …, 2021 - journals.lww.com
… To understand similarities between urine, kidney, and bladder cells, our urine single-cell
dataset was integrated with a previously published kidney single-nucleus dataset and a
bladder single-cell dataset. Two approaches were used for the integration: (1) the Harmony
method, 21 (2) and the anchor strategy. The Harmony method, as previously described, first
places cells into multiple subset clusters then projects cells to a shared embedding, in which
cells are grouped by cell type rather than … To understand the origin of the urinary cells and …
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