Use of marginal distributions constrained optimization (MADCO) for accelerated 2D MRI relaxometry and diffusometry
D Benjamini, PJ Basser - Journal of magnetic resonance, 2016 - Elsevier
Abstract Measuring multidimensional (eg, 2D) relaxation spectra in NMR and MRI clinical
applications is a holy grail of the porous media and biomedical MR communities. The main
bottleneck is the inversion of Fredholm integrals of the first kind, an ill-conditioned problem
requiring large amounts of data to stabilize a solution. We suggest a novel experimental
design and processing framework to accelerate and improve the reconstruction of such 2D
spectra that uses a priori information from the 1D projections of spectra, or marginal …
applications is a holy grail of the porous media and biomedical MR communities. The main
bottleneck is the inversion of Fredholm integrals of the first kind, an ill-conditioned problem
requiring large amounts of data to stabilize a solution. We suggest a novel experimental
design and processing framework to accelerate and improve the reconstruction of such 2D
spectra that uses a priori information from the 1D projections of spectra, or marginal …
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