Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions
The ban on the use of animals in testing cosmetic products has led to the development of
animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human
skin and is recommended as a replacement for skin. However, its usefulness in the
assessment of the permeation of cosmetics in in-use conditions remains unverified. No data
have been published on its comparative performance with the membrane of choice, porcine
skin. The comparative permeability characteristics of Strat-M® and porcine skin were …
animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human
skin and is recommended as a replacement for skin. However, its usefulness in the
assessment of the permeation of cosmetics in in-use conditions remains unverified. No data
have been published on its comparative performance with the membrane of choice, porcine
skin. The comparative permeability characteristics of Strat-M® and porcine skin were …
[PDF][PDF] Usefulness of Artificial Membrane, Strat-M®, in the Assessment of Drug Permeation from Complex Vehicles in Finite Dose Conditions
K Sugibayashi - academia.edu
The ban on the use of animals in testing cosmetic products has led to the development of
animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human
skin and is recommended as a replacement for skin. However, its usefulness in the
assessment of the permeation of cosmetics in in-use conditions remains unverified. No data
have been published on its comparative performance with the membrane of choice, porcine
skin. The comparative permeability characteristics of Strat-M® and porcine skin were …
animal-free in vitro methods. Strat-M® is an artificial membrane engineered to mimic human
skin and is recommended as a replacement for skin. However, its usefulness in the
assessment of the permeation of cosmetics in in-use conditions remains unverified. No data
have been published on its comparative performance with the membrane of choice, porcine
skin. The comparative permeability characteristics of Strat-M® and porcine skin were …
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