Utilization of hepatitis C virus-positive donors in kidney transplantation
Current opinion in organ transplantation, 2023•journals.lww.com
… Direct-acting antivirals (DAA) have transformed kidney transplantation by increasing the
donor pool from hepatitis C virus (HCV)-infected donors and allowing HCV nucleic acid
amplification testing (NAT) donor-positive/recipient-negative (D+/R-) transplantation over the last
7 years. Willingness to accept kidneys from HCV-infected donors and timing/duration of DAA
therapy have been evolving. … In this article, we review recent publications and the OPTN data
shedding light on aspects like disparities in utilization and willingness to accept HCV-infected …
donor pool from hepatitis C virus (HCV)-infected donors and allowing HCV nucleic acid
amplification testing (NAT) donor-positive/recipient-negative (D+/R-) transplantation over the last
7 years. Willingness to accept kidneys from HCV-infected donors and timing/duration of DAA
therapy have been evolving. … In this article, we review recent publications and the OPTN data
shedding light on aspects like disparities in utilization and willingness to accept HCV-infected …
Summary
Further studies are needed to evaluate long-term outcomes of HCV NAT D+/R− transplantation and the best course of DAA treatment.
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