Atypical furunculosis is a problem in farming of salmonids and various other fish species caused by a heterogeneous group of atypical Aeromonas salmonicida strains. Winter ulcer is a disease of salmonids and cod caused by Moritella viscosa, but a number of fish species are susceptible to the infection. Vaccines are available against atypical furunculosis of salmonids, but their efficacy is dependent on the characteristics of the infective strain. Vaccines for non-salmonid fish are currently not commercially available. Furunculosis vaccines for salmon can induce cross protection against some atypical A. salmonicida infections and only in some fish species. Polyvalent injection vaccines based on inactivated bacterial cells are available against winter ulcer disease of salmonids. Outbreaks of winter ulcer disease in vaccinated salmon are, however, continuously reported.