[PDF][PDF] Validation of Housekeeping Genes in the Brains of Rats Submitted to Chronic Intermittent
Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent nocturnal
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated
with several complications, such as diabetes, hypertension and obesity. Quantitative real-
time PCR has been performed in previous OSA-related studies; however, these studies
were not validated using proper reference genes. We have examined the effects of chronic
intermittent hypoxia (CIH), which is an experimental model mainly of cardiovascular …
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated
with several complications, such as diabetes, hypertension and obesity. Quantitative real-
time PCR has been performed in previous OSA-related studies; however, these studies
were not validated using proper reference genes. We have examined the effects of chronic
intermittent hypoxia (CIH), which is an experimental model mainly of cardiovascular …
Validation of housekeeping genes in the brains of rats submitted to chronic intermittent hypoxia, a sleep apnea model
Obstructive sleep apnea (OSA) is a syndrome characterized by intermittent nocturnal
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated
with several complications, such as diabetes, hypertension and obesity. Quantitative real-
time PCR has been performed in previous OSA-related studies; however, these studies
were not validated using proper reference genes. We have examined the effects of chronic
intermittent hypoxia (CIH), which is an experimental model mainly of cardiovascular …
hypoxia, sleep fragmentation, hypercapnia and respiratory effort, and it has been associated
with several complications, such as diabetes, hypertension and obesity. Quantitative real-
time PCR has been performed in previous OSA-related studies; however, these studies
were not validated using proper reference genes. We have examined the effects of chronic
intermittent hypoxia (CIH), which is an experimental model mainly of cardiovascular …
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