Ventilation and neurochemical changes during µ-opioid receptor activation or blockade of excitatory receptors in the hypoglossal motor nucleus of goats

TM Langer III, SE Neumueller… - Journal of applied …, 2017 - journals.physiology.org
Neuromodulator interdependence posits that changes in one or more neuromodulators are
compensated by changes in other modulators to maintain stability in the respiratory control
network. Herein, we studied compensatory neuromodulation in the hypoglossal motor
nucleus (HMN) after chronic implantation of microtubules unilaterally (n= 5) or bilaterally (n=
5) into the HMN. After recovery, receptor agonists or antagonists in mock cerebrospinal fluid
(mCSF) were dialyzed during the awake and non-rapid eye movement (NREM) sleep states …

Ventilation and neurochemical changes during µ-opioid receptor activation or blockade of excitatory receptors in the hypoglossal motor nucleus of goats 2

MR Talwar, L Pan, HV Forster, HV Forster - 2017 - journals.physiology.org
Neuromodulator interdependence posits that changes in one or more neuromodulators are
31 compensated by changes in other modulators to maintain stability in the respiratory
control 32 network. Herein, we studied compensatory neuromodulation in the hypoglossal
motor nucleus 33 (HMN) after chronic implantation of microtubules unilaterally (n= 5) or
bilaterally (n= 5) into the 34 HMN. After recovery, receptor agonists or antagonists in mock
cerebrospinal fluid (mCSF) were 35 dialyzed during the awake and NREM sleep state …
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