The aim: The purpose of this article is to identify through the analysis of biographical and scientific Sofia Okunevska-Morachevska, Sofia Parfanovych and Volodymyra Krushelnytska common features of personal and professional development to understand the scientific, social and cultural parts of their activities in the context of the history of national medical tradition.

Materials and methods: We will try to consider in general terms the life and professional path of Sofia Okunevska-Morachevska, Sofia Parfanovych, Volodymyra Krushelnytska, highlighting common features and analyzing them in contexts of social, political, and cultural features of the era. Conclusions: Analyzing the biographical milestones and scientific achievements of women physicians in Western Ukraine in the late XIX–early XX century, we concluded that these personalities of Ukrainian medicine can be combined with a number of characteristics, thus demonstrating the continuity and longevity of the national female medical elite in Ukraine.